ExoticRx · exoticrx.com/drugs/prednisolone
Delta-Cortef, Prelone
Binds intracellular glucocorticoid receptors, modulating gene transcription. Suppresses inflammatory and immune responses at multiple levels.
PU/PD, polyphagia, weight gain, iatrogenic Cushing's. Immunosuppression risk. GI ulceration (especially with NSAIDs). Do not abruptly discontinue after chronic use. Cats require prednisolone (not prednisone).
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 8 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–1 mg/kg | q12-24h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | PO | 2–4 mg/kg | q12h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.