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Mycophenolate Mofetil

CellCept

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Routes

POIV

Indications

IMHAImmune-mediated diseasesimmune-mediated skin diseasemyasthenia gravis

Mechanism of Action

Inhibits inosine monophosphate dehydrogenase, selectively blocking de novo purine synthesis in lymphocytes (which lack the salvage pathway).

Side effects & warnings

GI side effects common (diarrhea, vomiting). More selective immunosuppression than azathioprine. Monitor CBC. Teratogenic. Used for immune-mediated hemolytic anemia, myasthenia gravis, and transplant rejection.

Species with Mycophenolate Mofetil dosing data (2 dose rules)

Evidence levels across 2 dose rules

Moderate×1Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Papich Handbook of Veterinary Drugs, 5th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO10–20 mg/kgq12hModeratePlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)PO10 mg/kgq12hWeakPapich Handbook of Veterinary Drugs, 5th Ed

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