Skip to main content

Prednisolone for Cattle

Prednisolone is used in cattle for allergic reactions, Anti-inflammatory, Anti-inflammatory/Immunosuppressive, Immunosuppressive. Routes documented in cattle: PO, IV, IM. ExoticRx tracks Prednisolone dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Delta-Cortef, Prelone

Dose rules — sign in to view

Cited dose rules for Prednisolone in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: Carpenter's Exotic Animal Formulary, 6th Ed; ExoticRx 2026 (ferret dosing guide); Carpenter 6e; ExoticRx 2026 (hedgehog dosing guide); …

Mechanism of action

Binds intracellular glucocorticoid receptors, modulating gene transcription. Suppresses inflammatory and immune responses at multiple levels.

Side effects & warnings

PU/PD, polyphagia, weight gain, iatrogenic Cushing's. Immunosuppression risk. GI ulceration (especially with NSAIDs). Do not abruptly discontinue after chronic use. Cats require prednisolone (not prednisone).

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Prednisolone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.