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Ilunocitinib

Greylan

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Routes

PO

Indications

allergic pruritusAtopic dermatitis

Mechanism of Action

Selective Janus kinase 1 (JAK1) inhibitor that blocks cytokine signaling pathways involved in pruritus and inflammation, reducing itch and allergic skin inflammation in dogs.

Side effects & warnings

New veterinary JAK inhibitor with limited post-market data. Monitor CBC and liver values. May increase susceptibility to infections. Similar class warnings to oclacitinib.

Species with Ilunocitinib dosing data (1 dose rule)

Evidence levels across 1 dose rule

Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · FDA conditional approval data; FDA openFDA Adverse Event Database

Sample dosing (1 of 1 cited rule)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO0.6–1.8 mg/kgq24hModerateFDA conditional approval data; FDA openFDA Adverse Event Database

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