ExoticRx · exoticrx.com/drugs/prednisone
Prednisone
Deltasone
Drug Class
Routes
Indications
Mechanism of Action
Prodrug converted to prednisolone by the liver. Modulates gene transcription via glucocorticoid receptors, suppressing inflammatory/immune responses.
Side effects & warnings
INEFFECTIVE in cats (cannot convert to prednisolone — use prednisolone instead). PU/PD, polyphagia. GI ulceration. Iatrogenic Cushing's with chronic use. Taper when discontinuing.
Species with Prednisone dosing data (2 dose rules)
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published primary source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 2 cited rules)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–1 mg/kg | q12-24h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | PO | 2–4 mg/kg | q12h initially | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.