ExoticRx · exoticrx.com/drugs/magnesium-sulfate-injectable
Magnesium Sulfate Injectable
MgSO4
Drug Class
Routes
Indications
Mechanism of Action
Essential cofactor for >300 enzymatic reactions. Membrane stabilizer, smooth muscle relaxant, and NMDA receptor antagonist.
Side effects & warnings
Rapid IV push can cause hypotension, bradycardia, respiratory depression. Monitor reflexes and respiratory rate. Reduce dose in renal impairment.
Species with Magnesium Sulfate Injectable dosing data (2 dose rules)
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published primary source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Constant rate infusion (CRI)
Magnesium Sulfate Injectable CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.15–0.3 mEq/kgCRI over 12-24 hours | Hypomagnesemia, refractory ventricular arrhythmias | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 0.15–0.3 mEq/kgCRI over 12-24 hours | Hypomagnesemia, refractory arrhythmias | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
- Dog (Domestic)IV0.15–0.3 mEq/kgCRI over 12-24 hours
Hypomagnesemia, refractory ventricular arrhythmias
ModeratePlumb's Veterinary Drug Handbook, 9th Ed - Cat (Domestic)IV0.15–0.3 mEq/kgCRI over 12-24 hours
Hypomagnesemia, refractory arrhythmias
ModeratePlumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 2 cited rules)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.15–0.3 mEq/kg | CRI over 12-24 hours | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 0.15–0.3 mEq/kg | CRI over 12-24 hours | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.