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Cisapride Compounded Oral

Propulsid Compounded

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Miscellaneous

Routes

PO

Indications

GI stasisMegacolon/Chronic constipation

Mechanism of Action

Serotonin 5-HT4 receptor agonist that enhances acetylcholine release from the myenteric plexus, stimulating gastric emptying and colonic motility.

Side effects & warnings

Withdrawn from human market (cardiac arrhythmias) but available as veterinary compounded product. QT prolongation risk — avoid with other QT-prolonging drugs. Monitor ECG.

Species with Cisapride Compounded Oral dosing data (2 dose rules)

Evidence levels across 2 dose rules

Strong×1Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed; JFMS Constipation Review

Sample dosing (1 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Cat (Domestic)PO0.5–1 mg/kgq8-12h before mealsStrongPlumb's Veterinary Drug Handbook, 9th Ed; JFMS Constipation Review

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Other formulations of Cisapride