ExoticRx · exoticrx.com/drugs/magnesium-sulfate
MgSO4, Epsom Salt(injectable)
Essential electrolyte. Blocks neuromuscular transmission, stabilizes cardiac membranes, and causes smooth muscle relaxation. Cofactor for 300+ enzymes.
Treatment for hypomagnesemia, torsades de pointes, and eclampsia. Slow IV infusion. Respiratory depression at high levels. Monitor ECG and reflexes. Antidote: calcium gluconate.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Magnesium Sulfate CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.15–0.3 mEq/kgIV CRI over 15-60 min | Torsades de pointes, hypomagnesemia | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 0.15–0.3 mEq/kgCRI over 24h | Hypomagnesemia, refractory seizures | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Torsades de pointes, hypomagnesemia
Hypomagnesemia, refractory seizures
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.15–0.3 mEq/kg | IV CRI over 15-60 min | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 0.15–0.3 mEq/kg | CRI over 24h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.