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Vinblastine

Velban

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Oncology

Routes

IV

Indications

Mast cell tumors

Mechanism of Action

Binds tubulin dimers preventing microtubule assembly. Arrests mitosis in metaphase. M-phase specific. Related to vincristine.

Side effects & warnings

VESICANT — severe tissue necrosis with extravasation. Myelosuppression (neutropenia nadir 5-7 days). Used for mast cell tumors. Less neurotoxic than vincristine.

Species with Vinblastine dosing data (1 dose rule)

Dog (Domestic)

Evidence levels across 1 dose rule

Strong×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 1 cited rule)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)IV2 mg/m2q7-14 daysStrongPlumb's Veterinary Drug Handbook, 9th Ed

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Calculate Dosage for Vinblastine