ExoticRx · exoticrx.com/drugs/bleomycin
Blenoxane
Generates free radicals that cause DNA strand breaks and inhibit DNA synthesis. Cell cycle specific for G2 and M phases. Concentrated in skin and lung tissue.
Pulmonary fibrosis is dose-limiting and potentially fatal. Cumulative dose limit. Anaphylaxis risk — test dose recommended. Intralesional use for squamous cell carcinoma in cats.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 10 mg/kg | IV q7-21 days (10 units/m2) | Weak | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
| Cat (Domestic) | Intralesional | 0.5–1 mg/kg | Intralesional injection q1-2 weeks | Moderate | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.