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Tigilanol Tiglate

Stelfonta

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Oncology

Routes

INTRATUMORAL

Indications

Non-metastatic cutaneous mast cell tumors

Mechanism of Action

Activates protein kinase C, disrupting tumor vasculature and causing hemorrhagic necrosis. Also stimulates innate immune response against tumor cells.

Side effects & warnings

Dogs only. For non-metastatic mast cell tumors (cutaneous/SC). Wound at injection site expected — heals by second intention. Sedation/anesthesia required for injection.

Species with Tigilanol Tiglate dosing data (1 dose rule)

Evidence levels across 1 dose rule

Strong×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 1 cited rule)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)INTRATUMORAL0 see notesSingle treatment; may repeat once at day 28StrongPlumb's Veterinary Drug Handbook, 9th Ed

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