ExoticRx · exoticrx.com/drugs/proligestone
Proligestone
Delvosteron, Covinan
Drug Class
Routes
Indications
Mechanism of Action
14-alpha,17-alpha-progesterone derivative that suppresses estrus by inhibiting gonadotropin release. Long-acting depot injection.
Side effects & warnings
Not available in US. Risk of pyometra and mammary changes. Local reactions at injection site. Do not use in animals with reproductive disorders.
Species with Proligestone dosing data (2 dose rules)
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published primary source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 2 cited rules)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 10–33 mg/kg | Single injection; repeat q5-6 months | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | SC | 10–33 mg/kg | Single injection; repeat q4-5 months | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.