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Estriol

Incurin

Calculate dosage
Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Reproductive

Routes

PO

Indications

Post-spay urinary incontinenceUrinary incontinence (spay incontinence)

Mechanism of Action

Short-acting natural estrogen that increases urethral sphincter tone and mucosal sensitivity. Minimal systemic estrogenic effects compared to other estrogens.

Side effects & warnings

Lower risk of bone marrow suppression than other estrogens. Vulvar swelling and attracting males possible. Use lowest effective dose.

Species with Estriol dosing data (2 dose rules)

Dog (Domestic)Rabbit (Domestic)

Evidence levels across 2 dose rules

Strong×1Anecdotal×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO0.025–0.05 mg/kgq24h for 14 days, then lowest effective doseStrongPlumb's Veterinary Drug Handbook, 9th Ed

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Calculate Dosage for Estriol