ExoticRx · exoticrx.com/drugs/masitinib
Masivet, Kinavet
Selectively inhibits c-Kit receptor tyrosine kinase, PDGFR, and Lyn kinase. Targets mast cell tumor growth signaling. Also inhibits FGFR3.
Approved for non-resectable grade II/III mast cell tumors with confirmed c-Kit mutation. GI upset, neutropenia, protein-losing nephropathy. Monitor CBC and urinalysis.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 12.5 mg/kg | q24h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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