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Cytarabine

Cytosar-U

Calculate dosage
Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Oncology

Routes

IVSC

Indications

GME (granulomatous meningoencephalitis)

Mechanism of Action

Converted to ara-CTP which inhibits DNA polymerase and incorporates into DNA causing chain termination. S-phase specific.

Side effects & warnings

Used for lymphoma/leukemia protocols and GME. Myelosuppression dose-limiting. SC CRI protocol for GME (cytarabine arabinoside). Handle with chemotherapy precautions.

Species with Cytarabine dosing data (1 dose rule)

Evidence levels across 1 dose rule

Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 1 cited rule)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)SC50 mg/m2SC q12h x 2 days, repeat q3 weeksModeratePlumb's Veterinary Drug Handbook, 9th Ed

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