ExoticRx · exoticrx.com/drugs/cidofovir-systemic
Cidofovir Systemic
Vistide
Drug Class
Routes
Indications
Mechanism of Action
Nucleotide analogue that inhibits viral DNA polymerase. Does not require viral kinase activation. Active against CMV, adenovirus, polyomavirus, poxviruses.
Side effects & warnings
Severely nephrotoxic — must co-administer probenecid and IV hydration. Neutropenia. Ocular toxicity. Monitor renal function closely.
Species with Cidofovir Systemic dosing data (2 dose rules)
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published primary source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 2 cited rules)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 5 mg/kg | Once weekly x 2, then q2wk | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 5 mg/kg | Once weekly x 2, then q2wk | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.