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Acyclovir

Zovirax

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antiviral

Routes

POIVTopical

Indications

FHV-1 (not first-line)Psittacine herpesvirus

Mechanism of Action

Nucleoside analog selectively phosphorylated by viral thymidine kinase. Inhibits viral DNA polymerase. Active against herpesviruses.

Side effects & warnings

Used for equine herpesvirus and some avian herpesviruses. Limited efficacy for FHV-1 in cats (famciclovir preferred). Nephrotoxicity with IV form — ensure hydration. Crystalluria.

Species with Acyclovir dosing data (2 dose rules)

African Grey ParrotCat (Domestic)

Evidence levels across 2 dose rules

Weak×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Cat (Domestic)PO10–25 mg/kgq8hWeakPlumb's Veterinary Drug Handbook, 9th Ed

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