ExoticRx · exoticrx.com/drugs/brincidofovir
Brincidofovir
Tembexa
Drug Class
Routes
Indications
Mechanism of Action
Lipid conjugate of cidofovir. Converted intracellularly to cidofovir diphosphate which inhibits viral DNA polymerase. Broad dsDNA virus activity.
Side effects & warnings
GI upset (diarrhea, nausea). Less nephrotoxic than IV cidofovir. Approved for smallpox. Potential use for adenovirus, CMV. No veterinary data.
Species with Brincidofovir dosing data (2 dose rules)
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published primary source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 2 cited rules)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | Once weekly | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 1–2 mg/kg | Once weekly | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.