ExoticRx · exoticrx.com/drugs/xylazine
Rompun, AnaSed
Alpha-2 adrenergic agonist causing dose-dependent sedation, analgesia, and muscle relaxation. Also activates peripheral alpha-2 receptors causing vasoconstriction and bradycardia.
Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 8 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | 0.5–1 mg/kg | Single dose | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IM | 0.5–1 mg/kg | Single dose | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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