Xylazine for Swine
Xylazine is used in swine for Anaesthesia (with ketamine), analgesia, chemical restraint, emesis induction. Routes documented in swine: IV, IM, SC. ExoticRx tracks Xylazine dosing for swine from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.
Trade names: Rompun, AnaSed
Dose rules — sign in to view
Cited dose rules for Xylazine in swine are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.
Mechanism of action
Alpha-2 adrenergic agonist causing dose-dependent sedation, analgesia, and muscle relaxation. Also activates peripheral alpha-2 receptors causing vasoconstriction and bradycardia.
Side effects & warnings
Profound bradycardia and vomiting (especially cats). Cats more sensitive than dogs. Reversible with atipamezole or yohimbine. Avoid in horses with colic (ileus). 100mg/ml for large animals only.
Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Xylazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.
Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.