ExoticRx · exoticrx.com/drugs/voriconazole
Vfend
Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase), blocking ergosterol synthesis. Broader spectrum than fluconazole including Aspergillus.
Drug of choice for aspergillosis. Hepatotoxic — monitor liver enzymes. Many CYP-mediated drug interactions. Visual disturbances in humans. Non-linear pharmacokinetics in some species.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 3–4 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 5–6 mg/kg | q12h | Weak | Papich Handbook of Veterinary Drugs, 5th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.