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Amphotericin B Lipid Complex

Abelcet

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antifungal

Routes

IV

Indications

Systemic fungal infectionsSystemic fungal infections (blastomycosis, histoplasmosis, aspergillosis)

Mechanism of Action

Binds ergosterol creating membrane pores. Lipid complex formulation reduces nephrotoxicity by preferentially distributing to RES tissues.

Side effects & warnings

Less nephrotoxic than conventional amphotericin B but still significant. Infusion reactions. Monitor renal function and electrolytes.

Species with Amphotericin B Lipid Complex dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Evidence levels across 2 dose rules

Moderate×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)IV1–3 mg/kgq48h or 3x/weekModeratePlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)IV1–1.5 mg/kgq48h or 3x/weekModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Calculate Dosage for Amphotericin B Lipid Complex