ExoticRx · exoticrx.com/drugs/procainamide
Pronestyl, Procanbid
Class IA antiarrhythmic blocking fast sodium channels. Prolongs action potential duration and effective refractory period in atria and ventricles.
GI upset common. Drug-induced lupus (SLE) with chronic use. Monitor CBC, ANA. N-acetylprocainamide (NAPA) metabolite has Class III activity.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Procainamide CRI dose rule from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 2–4 mg/kgIV bolus over 3-5 min, then CRI 10-40 mcg/kg/min | Ventricular tachyarrhythmias | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Ventricular tachyarrhythmias
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 2–4 mg/kg | IV bolus over 3-5 min, then CRI 10-40 mcg/kg/min | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | PO | 10–30 mg/kg | q6-8h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.