Skip to main content

Amlodipine Besylate

Norvasc, Amodip

Calculate dosage
Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Cardiovascular

Routes

PO

Indications

Hypertension (with renal disease)Systemic hypertension

Mechanism of Action

Selectively blocks L-type calcium channels in vascular smooth muscle causing vasodilation. Reduces systemic vascular resistance and blood pressure.

Side effects & warnings

First-line antihypertensive in cats. Dose-dependent hypotension. Gingival hyperplasia reported in dogs. Monitor blood pressure regularly.

Species with Amlodipine Besylate dosing data (3 dose rules)

Cat (Domestic)Dog (Domestic)Rabbit (Domestic)

Evidence levels across 3 dose rules

Moderate×1Strong×1Extrapolated×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 3 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 3 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO0.1–0.5 mg/kgq24hModeratePlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)PO0.625–1.25 mg/kgq24hStrongPlumb's Veterinary Drug Handbook, 9th Ed

Upgrade for Full Details

Upgrade to Pro or Student to access full drug details including mechanism of action, warnings, dose ranges, and frequency.

View Plans

More Cardiovascular drugs

Calculate Dosage for Amlodipine Besylate