Question 1

What is Amlodipine used for?

Accepted Answer

Amlodipine is indicated for: CKD-associated hypertension, Hyperthyroid-associated hypertension, Pulmonary hypertension adjunct, Systemic hypertension.

Question 2

What routes can Amlodipine be administered by?

Accepted Answer

Available routes: PO.

Question 3

Which species have cited Amlodipine dosing data?

Accepted Answer

Amlodipine dosing in the ExoticRx formulary covers 3 species: Cat (Domestic), Dog (Domestic), Rabbit (Domestic).

Question 4

Is Amlodipine a controlled substance?

Accepted Answer

Amlodipine is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Amlodipine?

Accepted Answer

First-line antihypertensive in cats. Monitor blood pressure during dose titration. Hypotension at excessive doses. May cause gingival hyperplasia with prolonged use.

Question 6

What are the side effects of Amlodipine?

Accepted Answer

First-line antihypertensive in cats. Monitor blood pressure during dose titration. Hypotension at excessive doses. May cause gingival hyperplasia with prolonged use.

Question 7

How does Amlodipine work?

Accepted Answer

Dihydropyridine calcium channel blocker. Relaxes vascular smooth muscle, reducing peripheral vascular resistance and systemic blood pressure.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	0.05–0.1 mg/kg	q12-24h	Weak	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	PO	0.05–0.1 mg/kg	q24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Amlodipine

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Amlodipine dosing data (12 dose rules)

Evidence levels across 12 dose rules

Backed by 2 published primary sources

Sample dosing (2 of 12 cited rules)

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