Question 1

What is Omalizumab used for?

Accepted Answer

Omalizumab is indicated for: atopic dermatitis, Severe allergic asthma, Severe feline asthma (investigational).

Question 2

What routes can Omalizumab be administered by?

Accepted Answer

Available routes: SC.

Question 3

Which species have cited Omalizumab dosing data?

Accepted Answer

Omalizumab dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Omalizumab a controlled substance?

Accepted Answer

Omalizumab is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Omalizumab?

Accepted Answer

Anaphylaxis risk — observe post-injection. Very expensive. Species-specific antibodies needed for veterinary use. Investigational.

Question 6

What are the side effects of Omalizumab?

Accepted Answer

Anaphylaxis risk — observe post-injection. Very expensive. Species-specific antibodies needed for veterinary use. Investigational.

Question 7

How does Omalizumab work?

Accepted Answer

Humanized monoclonal antibody that binds free IgE, preventing attachment to high-affinity IgE receptors on mast cells and basophils, reducing allergic inflammation.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	SC	1–5 mg/kg	q2-4 weeks	Extrapolated	Veterinary Immunology Literature Review
Cat (Domestic)	SC	1–5 mg/kg	q2-4 weeks	Extrapolated	Veterinary Immunology Literature Review

Omalizumab

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Omalizumab dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published primary source

Sample dosing (2 of 2 cited rules)

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