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Aminophylline

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Respiratory

Routes

POIVIM

Indications

Acute bronchospasmBronchodilationchronic bronchitisCollapsing trachea adjunctFeline asthma (adjunct bronchodilator)

Mechanism of Action

Phosphodiesterase inhibitor and adenosine receptor antagonist. Relaxes bronchial smooth muscle, stimulates respiratory drive, and has mild diuretic effect.

Side effects & warnings

Narrow therapeutic index. Monitor for tachycardia, GI upset, CNS stimulation, and seizures. Avoid concurrent fluoroquinolones (decreased metabolism). IV administration must be slow.

Species with Aminophylline dosing data (16 dose rules)

Evidence levels across 16 dose rules

Moderate×10Extrapolated×6

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 16 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 5 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)IV5–10 mg/kgq8hModeratePlumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)IV5–10 mg/kgq8hModeratePlumb's Veterinary Drug Handbook, 9th Ed

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