Question 1

What is Ammonium Chloride used for?

Accepted Answer

Ammonium Chloride is indicated for: Struvite dissolution (urinary acidification), Urinary acidification.

Question 2

What routes can Ammonium Chloride be administered by?

Accepted Answer

Available routes: PO, IV.

Question 3

Which species have cited Ammonium Chloride dosing data?

Accepted Answer

Ammonium Chloride dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Ammonium Chloride a controlled substance?

Accepted Answer

Ammonium Chloride is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Ammonium Chloride?

Accepted Answer

Used for metabolic alkalosis and struvite urolith prevention/dissolution. Contraindicated in hepatic insufficiency (ammonia cannot be metabolized). Monitor blood pH and electrolytes.

Question 6

What are the side effects of Ammonium Chloride?

Accepted Answer

Used for metabolic alkalosis and struvite urolith prevention/dissolution. Contraindicated in hepatic insufficiency (ammonia cannot be metabolized). Monitor blood pH and electrolytes.

Question 7

How does Ammonium Chloride work?

Accepted Answer

Metabolized by liver releasing HCl and producing systemic acidification. Excreted renally as acidifying ammonium ion.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	100–200 mg/kg	q12h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	PO	20–40 mg/kg	q12h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Ammonium Chloride

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Ammonium Chloride dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published primary source

Sample dosing (2 of 2 cited rules)

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