ExoticRx · exoticrx.com/drugs/aminocaproic-acid-oral
Amicar
Competitively inhibits plasminogen activation, preventing fibrinolysis. Stabilizes existing clots by blocking conversion of plasminogen to plasmin.
May cause GI upset. Contraindicated with DIC. Monitor for thrombosis. Used in dogs for degenerative myelopathy (off-label) and bleeding disorders.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 15–40 mg/kg | q8h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 50–100 mg/kg | q6-8h IV or PO | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
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