ExoticRx · exoticrx.com/drugs/isosorbide-mononitrate
Imdur, Monoket
Active metabolite of isosorbide dinitrate that releases nitric oxide, dilating venous capacitance vessels and reducing cardiac preload.
Similar to isosorbide dinitrate but with more predictable oral bioavailability. Tolerance still develops. Hypotension possible.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–2 mg/kg | q12-24h (ER formulation) | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 0.5–1 mg/kg | q12-24h | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
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