Question 1

What is Clopidogrel used for?

Accepted Answer

Clopidogrel is indicated for: Antiplatelet therapy, Prevention of arterial thromboembolism.

Question 2

What routes can Clopidogrel be administered by?

Accepted Answer

Available routes: PO.

Question 3

Which species have cited Clopidogrel dosing data?

Accepted Answer

Clopidogrel dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Clopidogrel a controlled substance?

Accepted Answer

Clopidogrel is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Clopidogrel?

Accepted Answer

Primary use in cats: prevention of arterial thromboembolism (ATE) in cardiomyopathy. Give with food. Bleeding risk. Takes 3-5 days for full antiplatelet effect. Preferred over aspirin in cats.

Question 6

What are the side effects of Clopidogrel?

Accepted Answer

Primary use in cats: prevention of arterial thromboembolism (ATE) in cardiomyopathy. Give with food. Bleeding risk. Takes 3-5 days for full antiplatelet effect. Preferred over aspirin in cats.

Question 7

How does Clopidogrel work?

Accepted Answer

Irreversibly blocks the P2Y12 ADP receptor on platelet surface, preventing ADP-mediated platelet activation and aggregation.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	1–2 mg/kg	q24h	Moderate	Papich Handbook of Veterinary Drugs, 5th Ed
Cat (Domestic)	PO	18.75 mg/kg	q24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Clopidogrel

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Clopidogrel dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by 2 published primary sources

Sample dosing (2 of 2 cited rules)

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