ExoticRx · exoticrx.com/drugs/clemastine
Clemastine
Tavist, Dayhist
Drug Class
Routes
Indications
Mechanism of Action
Competitive H1 histamine receptor antagonist that blocks histamine-mediated allergic responses including pruritus, urticaria, and rhinitis.
Side effects & warnings
Sedation is common. Anticholinergic effects (dry mouth, urinary retention). May be more effective than diphenhydramine for canine atopic dermatitis.
Species with Clemastine dosing data (2 dose rules)
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published primary source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 2 cited rules)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.05–0.1 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 0.34–0.67 mg per cat | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.