Question 1

What is Cilostazol used for?

Accepted Answer

Cilostazol is indicated for: Peripheral vascular disease, Thromboembolism prevention adjunct, thrombosis adjunct.

Question 2

What routes can Cilostazol be administered by?

Accepted Answer

Available routes: PO.

Question 3

Which species have cited Cilostazol dosing data?

Accepted Answer

Cilostazol dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Cilostazol a controlled substance?

Accepted Answer

Cilostazol is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Cilostazol?

Accepted Answer

Contraindicated in heart failure. Headache, diarrhea. Avoid with CYP3A4 and CYP2C19 inhibitors. Limited veterinary use for peripheral vascular disease.

Question 6

What are the side effects of Cilostazol?

Accepted Answer

Contraindicated in heart failure. Headache, diarrhea. Avoid with CYP3A4 and CYP2C19 inhibitors. Limited veterinary use for peripheral vascular disease.

Question 7

How does Cilostazol work?

Accepted Answer

Selective phosphodiesterase-3 inhibitor that increases cAMP in platelets and vascular smooth muscle, inhibiting platelet aggregation and causing vasodilation.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	2–5 mg/kg	q12h	Weak	Veterinary Hematology Literature Review
Cat (Domestic)	PO	2–5 mg/kg	q12h	Extrapolated	Veterinary Hematology Literature Review

Cilostazol

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Cilostazol dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published primary source

Sample dosing (2 of 2 cited rules)

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