Question 1

What is Tacrolimus Ophthalmic used for?

Accepted Answer

Tacrolimus Ophthalmic is indicated for: Eosinophilic keratitis refractory to cyclosporine, KCS refractory to cyclosporine.

Question 2

What routes can Tacrolimus Ophthalmic be administered by?

Accepted Answer

Available routes: Ophthalmic.

Question 3

Which species have cited Tacrolimus Ophthalmic dosing data?

Accepted Answer

Tacrolimus Ophthalmic dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Tacrolimus Ophthalmic a controlled substance?

Accepted Answer

Tacrolimus Ophthalmic is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Tacrolimus Ophthalmic?

Accepted Answer

Used for KCS refractory to cyclosporine ophthalmic. Must be compounded. More effective than cyclosporine in some cases. Mild local irritation possible.

Question 6

What are the side effects of Tacrolimus Ophthalmic?

Accepted Answer

Used for KCS refractory to cyclosporine ophthalmic. Must be compounded. More effective than cyclosporine in some cases. Mild local irritation possible.

Question 7

How does Tacrolimus Ophthalmic work?

Accepted Answer

Calcineurin inhibitor 10-100x more potent than cyclosporine. Inhibits T-lymphocyte activation and proliferation, reducing lacrimal gland inflammation.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	Ophthalmic	0 mg/kg	Apply 0.02-0.03% ointment to affected eye(s) q12h	Strong	Gelatt KN, Veterinary Ophthalmology, 6th Ed
Cat (Domestic)	Ophthalmic	0 mg/kg	Apply 0.02% ointment to affected eye(s) q12h	Moderate	Gelatt KN, Veterinary Ophthalmology, 6th Ed

Tacrolimus Ophthalmic

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Tacrolimus Ophthalmic dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published primary source

Sample dosing (2 of 2 cited rules)

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