Question 1

What is Apraclonidine Ophthalmic used for?

Accepted Answer

Apraclonidine Ophthalmic is indicated for: Acute glaucoma (short-term IOP reduction), Pharmacologic testing (sympathetic denervation).

Question 2

What routes can Apraclonidine Ophthalmic be administered by?

Accepted Answer

Available routes: Ophthalmic.

Question 3

Which species have cited Apraclonidine Ophthalmic dosing data?

Accepted Answer

Apraclonidine Ophthalmic dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Apraclonidine Ophthalmic a controlled substance?

Accepted Answer

Apraclonidine Ophthalmic is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Apraclonidine Ophthalmic?

Accepted Answer

Tachyphylaxis develops with chronic use — best for short-term IOP reduction. May cause conjunctival blanching. Minimal systemic absorption.

Question 6

What are the side effects of Apraclonidine Ophthalmic?

Accepted Answer

Tachyphylaxis develops with chronic use — best for short-term IOP reduction. May cause conjunctival blanching. Minimal systemic absorption.

Question 7

How does Apraclonidine Ophthalmic work?

Accepted Answer

Selective alpha-2 adrenergic agonist that reduces aqueous humor production and enhances uveoscleral outflow, lowering intraocular pressure.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	Ophthalmic	0 mg/kg	1 drop affected eye q8h-q12h	Moderate	Gelatt KN, Veterinary Ophthalmology, 6th Ed
Cat (Domestic)	Ophthalmic	0 mg/kg	1 drop each eye; observe at 20, 45 min	Moderate	Gelatt KN, Veterinary Ophthalmology, 6th Ed

Apraclonidine Ophthalmic

Drug Class