ExoticRx · exoticrx.com/drugs/proparacaine-ophthalmic
Alcaine, Proparacaine HCl
Ester-type local anesthetic that stabilizes neuronal membranes by inhibiting sodium ion channels, preventing initiation and transmission of nerve impulses from the corneal surface.
Onset within 20 seconds, duration 15-20 minutes. Repeated use causes corneal epithelial toxicity. Never dispense for at-home use. Store refrigerated.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | 0 mg/kg | 1-2 drops; onset 20 sec, duration 15-20 min | Strong | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.