ExoticRx · exoticrx.com/drugs/phenylephrine
Neo-Synephrine
Selective alpha-1 adrenergic agonist causing vasoconstriction without direct cardiac stimulation. Increases SVR and blood pressure. Reflex bradycardia.
Pure vasopressor — no inotropic effect. Reflex bradycardia expected. Tissue necrosis with extravasation. Also used ophthalmically for mydriasis (2.5% — avoid 10% in small animals).
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Phenylephrine CRI dose rule from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.5–5 mcg/kg/minCRI | Refractory hypotension (vasopressor) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Refractory hypotension (vasopressor)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.5–5 mcg/kg/min | CRI | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Upgrade to Pro or Student to access full drug details including mechanism of action, warnings, dose ranges, and frequency.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.