ExoticRx · exoticrx.com/drugs/natamycin-ophthalmic
Natacyn
Polyene antifungal binding ergosterol in fungal cell membranes. First-line for fungal keratitis, especially Fusarium and Aspergillus.
Shake well. Poor corneal penetration — effective mainly for superficial fungal keratitis. Equine fungal keratitis common indication. Expensive.
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | 0 mg/kg | q2-4h initially, then q6h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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