Skip to main content

Moxidectin

ProHeart, Advantage Multi(combination), ProHeart 6, ProHeart 12

Calculate dosage
Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antiparasitic

Routes

POSCTOPICAL

Indications

botsencysted cyathostomesencysted cyathostominsGI nematodesGI nematodes including resistant HaemonchusGI strongylesHeartworm prevention (6- or 12-month)Internal and external parasitesStrongyles

Mechanism of Action

Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells. Sustained-release formulation provides 6- or 12-month heartworm prevention.

Side effects & warnings

Caution in MDR1-mutant dogs. ProHeart injection: risk of anaphylaxis (monitor 30 min post-injection). Test for heartworm before starting. Store properly.

Species with Moxidectin dosing data (7 dose rules)

Cattle (Beef/Dairy)Dog (Domestic)Goat (Caprine)Horse (Equine)Sheep (Ovine)

Evidence levels across 7 dose rules

Strong×5Moderate×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · FDA NADA Label
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 7 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 5 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)SC0.17 mg/kgq6-12monthsStrongPlumb's Veterinary Drug Handbook, 9th Ed

Upgrade for Full Details

Upgrade to Pro or Student to access full drug details including mechanism of action, warnings, dose ranges, and frequency.

View Plans

More Antiparasitic drugs

Calculate Dosage for Moxidectin