ExoticRx · exoticrx.com/drugs/morphine
Prototype full mu-opioid receptor agonist. Activates mu, kappa, and delta opioid receptors producing analgesia, sedation, and euphoria.
Histamine release with rapid IV injection (hypotension, bronchoconstriction — give slowly). Vomiting and defecation common initial effects. Respiratory depression. Cats: may cause excitation/dysphoria at higher doses. Controlled substance (Schedule II).
Controlled substance
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Morphine CRI dose rule from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.1–0.5 mg/kgq2-4h bolus or 0.1-0.3 mg/kg/h CRI | Severe pain, CRI | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Severe pain, CRI
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.1–0.5 mg/kg | q2-4h bolus or 0.1-0.3 mg/kg/h CRI | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | EPIDURAL | 0.1 mg/kg | Single injection | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.