ExoticRx · exoticrx.com/drugs/carprofen
Rimadyl, Novox
Preferentially inhibits COX-2, reducing prostaglandin synthesis at sites of inflammation while relatively sparing COX-1 (GI, renal, platelet).
Hepatotoxicity reported (especially Labrador Retrievers). Monitor liver enzymes. GI ulceration risk. Avoid in cats (limited safety data). Not for use with other NSAIDs.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2.2–4.4 mg/kg | q12-24h | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | SC | 4.4 mg/kg | Single dose preop | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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