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Milbemycin Oxime Injectable

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antiparasitic

Routes

SC

Indications

Heartworm prevention (6 or 12 months)

Mechanism of Action

Sustained-release moxidectin (ProHeart) microspheres providing 6 or 12 months of heartworm prevention. Potentiates glutamate-gated chloride channels.

Side effects & warnings

Single SC injection for 6-12 months heartworm prevention. Anaphylaxis risk (monitor 30 min post-injection). Not for dogs <12 months old. Must be administered by veterinarian.

Species with Milbemycin Oxime Injectable dosing data (1 dose rule)

Dog (Domestic)

Evidence levels across 1 dose rule

Strong×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published primary source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 1 cited rule)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 1 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)SC0 mg/kgOne injection q6 or q12 monthsStrongPlumb's Veterinary Drug Handbook, 9th Ed

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Calculate Dosage for Milbemycin Oxime Injectable