ExoticRx · exoticrx.com/drugs/midazolam
Midazolam
Versed
Drug Class
Routes
Indications
Mechanism of Action
Enhances GABA-A receptor activity, increasing chloride conductance. Provides anxiolysis, sedation, muscle relaxation, and anticonvulsant effects.
Side effects & warnings
May cause paradoxical excitement in healthy dogs when used alone. Water-soluble (less painful IM than diazepam). Respiratory depression at high doses. Flumazenil is the reversal agent.
Species with Midazolam dosing data (38 dose rules)
Controlled Substance
Controlled substance
Evidence levels across 38 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by 7 published primary sources
- · Carpenter 6e
- · Carpenter's Exotic Animal Formulary, 6th Ed
- · ExoticRx 2026 (chinchilla dosing guide); Carpenter 6e
- · ExoticRx 2026 (ferret dosing guide); Carpenter 6e
- · ExoticRx 2026 (hedgehog dosing guide); Carpenter 6e
- · ExoticRx 2026 (rat dosing guide); Carpenter 6e
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 38 cited rules)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 12 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | 0.2–0.5 mg/kg | once | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | IM | 0.2–0.5 mg/kg | once | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.