Question 1

What is Mavacoxib used for?

Accepted Answer

Mavacoxib is indicated for: Not approved, Osteoarthritis (long-term).

Question 2

What routes can Mavacoxib be administered by?

Accepted Answer

Available routes: PO.

Question 3

Which species have cited Mavacoxib dosing data?

Accepted Answer

Mavacoxib dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Mavacoxib a controlled substance?

Accepted Answer

Mavacoxib is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Mavacoxib?

Accepted Answer

Dogs only (EU-approved). Very long half-life — cannot rapidly discontinue if adverse effects. Not for dogs <12 months or <5kg. Monitor hepatic/renal. Maximum 7 doses (6.5 months).

Question 6

What are the side effects of Mavacoxib?

Accepted Answer

Dogs only (EU-approved). Very long half-life — cannot rapidly discontinue if adverse effects. Not for dogs <12 months or <5kg. Monitor hepatic/renal. Maximum 7 doses (6.5 months).

Question 7

How does Mavacoxib work?

Accepted Answer

Selective COX-2 inhibitor with extremely long half-life (44 days in dogs). Once-monthly dosing after initial loading.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	2 mg/kg	Day 0, Day 14, then monthly (max 7 doses)	Strong	BSAVA Small Animal Formulary, 10th Ed
Cat (Domestic)	PO	0 N/A	N/A	Extrapolated	BSAVA Small Animal Formulary, 10th Ed

Mavacoxib

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Mavacoxib dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published primary source

Sample dosing (2 of 2 cited rules)

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