Question 1

What is Maropitant used for?

Accepted Answer

Maropitant is indicated for: Acute vomiting, Motion sickness, visceral analgesia, vomiting.

Question 2

What routes can Maropitant be administered by?

Accepted Answer

Available routes: PO, SC, IV.

Question 3

Which species have cited Maropitant dosing data?

Accepted Answer

Maropitant dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Maropitant a controlled substance?

Accepted Answer

Maropitant is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Maropitant?

Accepted Answer

SC injection may sting (refrigerate prior). Dogs and cats. May mask signs of GI obstruction. Visceral analgesic properties make it useful as part of multimodal analgesia.

Question 6

What are the side effects of Maropitant?

Accepted Answer

SC injection may sting (refrigerate prior). Dogs and cats. May mask signs of GI obstruction. Visceral analgesic properties make it useful as part of multimodal analgesia.

Question 7

How does Maropitant work?

Accepted Answer

Blocks substance P at NK1 receptors in the vomiting center (CRTZ and nucleus tractus solitarius). Also provides visceral analgesia.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	2–8 mg/kg	q24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	SC	1 mg/kg	q24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Maropitant

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Maropitant dosing data (4 dose rules)

Evidence levels across 4 dose rules

Backed by a published primary source

Sample dosing (2 of 4 cited rules)

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Other formulations of Maropitant