Question 1

What is Mannitol used for?

Accepted Answer

Mannitol is indicated for: acute glaucoma, Cerebral edema, oliguric renal failure.

Question 2

What routes can Mannitol be administered by?

Accepted Answer

Available routes: IV.

Question 3

Which species have cited Mannitol dosing data?

Accepted Answer

Mannitol dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Mannitol a controlled substance?

Accepted Answer

Mannitol is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Mannitol?

Accepted Answer

Used for cerebral edema, acute glaucoma, and oliguric renal failure. Administer through filter (may crystallize). May cause volume overload initially. CONTRAINDICATED in pulmonary edema, dehydration, anuria.

Question 6

What are the side effects of Mannitol?

Accepted Answer

Used for cerebral edema, acute glaucoma, and oliguric renal failure. Administer through filter (may crystallize). May cause volume overload initially. CONTRAINDICATED in pulmonary edema, dehydration, anuria.

Question 7

How does Mannitol work?

Accepted Answer

Osmotic diuretic that draws water from intracellular and interstitial spaces into the intravascular compartment. Reduces intracranial and intraocular pressure.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IV	0.5–2 g/kg	q4-6h (max 3 doses in 24h)	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	IV	0.5–1.5 g/kg	q4-6h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Mannitol

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Mannitol dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published primary source

Sample dosing (2 of 2 cited rules)

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