ExoticRx · exoticrx.com/drugs/acetohydroxamic-acid
Acetohydroxamic Acid
Lithostat
Drug Class
Routes
Indications
Mechanism of Action
Irreversibly inhibits bacterial urease, preventing hydrolysis of urea to ammonia. Reduces urine pH and prevents struvite stone formation.
Side effects & warnings
Teratogenic — do not use in pregnant animals. GI upset and hemolytic anemia possible. Monitor CBC. Not a substitute for antibiotics in UTI.
Species with Acetohydroxamic Acid dosing data (2 dose rules)
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published primary source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 2 cited rules)
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 12.5 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 12.5 mg/kg | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.