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Allopurinol

Zyloprim, Aloprim

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Urinary

Routes

PO

Indications

Gout (uric acid nephropathy)Urate urolithiasis prevention

Mechanism of Action

Inhibits xanthine oxidase, reducing conversion of hypoxanthine to xanthine and xanthine to uric acid. Lowers serum and urinary urate levels.

Side effects & warnings

May cause xanthine urolithiasis if protein intake not controlled. Feed low-purine diet concurrently. Monitor uric acid levels and hepatic function.

Species with Allopurinol dosing data (2 dose rules)

Evidence levels across 2 dose rules

Strong×1Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 2 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO10–15 mg/kgq12hStrongPlumb's Veterinary Drug Handbook, 9th Ed

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