ExoticRx · exoticrx.com/drugs/lipid-emulsion-ile-20
Intralipid, ClinOleic
Creates a lipid sink in plasma that sequesters lipophilic drugs away from target tissues. May also enhance mitochondrial energy production in cardiac tissue.
For local anesthetic systemic toxicity (LAST), permethrin toxicity, and other lipophilic drug overdoses. Pancreatitis risk. Interferes with lab tests. Use 20% emulsion only.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Lipid Emulsion (ILE) 20% CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 1.5 ml/kgBolus 1min, CRI 0.25ml/kg/min x30-60m | Local anesthetic systemic toxicity (LAST)/Lipophilic drug overdose | Moderate | VECCS Guidelines; AACT Consensus on ILE |
| Cat (Domestic) | IV | 1.5–2 ml/kgBolus 1min, CRI 0.25ml/kg/min x30-60m | Permethrin toxicity/Lipophilic drug overdose | Moderate | VECCS Guidelines; JVECC Published Case Series |
Local anesthetic systemic toxicity (LAST)/Lipophilic drug overdose
Permethrin toxicity/Lipophilic drug overdose
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 1.5 ml/kg | Bolus 1min, CRI 0.25ml/kg/min x30-60m | Moderate | VECCS Guidelines; AACT Consensus on ILE |
| Cat (Domestic) | IV | 1.5–2 ml/kg | Bolus 1min, CRI 0.25ml/kg/min x30-60m | Moderate | VECCS Guidelines; JVECC Published Case Series |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.