ExoticRx · exoticrx.com/drugs/ketoconazole-topical
Nizoral Topical
Inhibits fungal lanosterol 14-alpha demethylase, disrupting ergosterol biosynthesis and fungal membrane integrity. Also has anti-inflammatory and antiseborrheic properties.
Effective for Malassezia dermatitis as shampoo. Leave on 10 minutes for contact time. May cause local irritation. Minimal systemic absorption from topical use.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Topical | 0 mg/kg | Bathe 2x weekly with shampoo; 10-min contact time | Strong | Miller WH, Small Animal Dermatology, 7th Ed |
| Cat (Domestic) | Topical | 0 mg/kg | Bathe 1-2x weekly; 10-min contact time | Moderate | Miller WH, Small Animal Dermatology, 7th Ed |
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